Selank should be used with clinician oversight, particularly in patients taking antidepressants, anxiolytics, stimulants, sleep medications, or other neuroactive drugs. Although published clinical research exists, long-term and large-scale safety data are more limited than for established psychiatric medications. Patients should also report unexpected mood changes, worsening anxiety, agitation, sleep disruption, or allergic symptoms. Your clinician will review your psychiatric history and current medication use before starting treatment, and any change to an existing prescription medication should be made by the clinician responsible for that medication rather than because Selank has been added.